Isaac's most Difficult Challenge has been beaten - The 30 Character Run
I Tried Isaac's HARDEST Challenge
Beating Isaac's HARDEST Seed .. I Regret it
I Beat Isaac's IMPOSSIBLE Challenge (Dads Home+)
I Beat the HARDEST Isaac Run. It was a mistake.
Getting Isaac's HARDEST Achievement...
After 318 Losses, Can I Finally Beat Isaac's Hardest Challenge? - Tainted Lost No Items
Isaac's "HARDEST" Challenge
Can I Beat The Binding of Isaac: Repentance Without Picking Up Items?
Top 5 Hardest Challenges in The Binding of Isaac: Repentance
How to beat Ultra Hard challenge easily | The Binding Of Isaac Repentance
The "HARDEST" Challenge in The Binding of Isaac
This Is What A 19 Hour Isaac Run Looks Like...
Finally Beating The Ultra Hard Challenge! - The Binding of Isaac: Repentance
Ranking Isaac CHALLENGES By Their UNLOCKS
Worlds FASTEST Isaac Repentance Run [WR] [Random Seed]
isaac challenges are the worst
Can I Beat EVERY BOSS IN ISAAC On The Same Run? - The Binding Of Isaac: Repentance #215
DO THESE CHALLENGES IN The Binding Of Isaac
The CREEPIEST Isaac Boss EVER! Cacophobia (Fiend Folio)
![Worlds FASTEST Isaac Repentance Run [WR] [Random Seed]](https://img.youtube.com/vi/4KthMPewJcU/0.jpg)
